IVF FAILURE: REASONS WHEN IN-VITRO DOESN’T WORK

Bayo Ajibola

ivf

Getting a child is a process that you as a human being have very little control over (even though it is your own body). Mother Nature always adds a little twist to the process. Sometimes conceiving may be hampered because of biological reasons.

Where you are unable to conceive due to fertility problems a number of fertility treatments are available. One of these treatments is known as In-Vitro Fertilization (IVF). It is performed by taking an egg and a sperm and bringing them together outside the body. The new embryo is then implanted back into the uterus.

There are times however that IVF does not lead to a baby. When this happens there are a few things that may be responsible.

Egg quality

The egg gives a large percentage of what is required for the formation and development of the embryo. When the sperm joins with the embryo a series of chemical reactions occur. A faulty egg may lead to a faulty embryo and therefore no baby. The better-looking an egg is (more symmetrical) the better the chances of it producing healthy embryo.

Egg quality and quantity reduces as time goes by. At 30 years of age the quality and quantity begins dwindling. It then goes a little faster after that to the extent that at 40 years only 10% of your eggs are available.

Sperm quality

The other requirement for the formation of an embryo is good sperm. Sperm with broken or damaged DNA will lead to the formation of an improper embryo. The sperm also has to be mature enough.

Things that can interfere with the quality of sperm include smoking, exposure to chemicals, presence of free radicals and sometimes even trauma to the testicles. Age is not really a big factor in men because men can sire children even in their 60s.

HCG Injection

HCG stands for Human Chorionic Gonadotropin. It makes the egg fertilizable by the sperm when the time comes. Since the egg is in a follicle HCG also assists with getting the egg free from the walls of the follicle.

If the HCG is given too early it can lead to the collection of very few mature eggs. If it is administered too late it lets theprogesterone level rise and this makes the endometrium not so friendly to the embryo.

Other reasons include a thin endometrial lining, a faulty transfer process or maybe problems in the lab. Whatever the cause may be, be sure to stay in close contact with your doctor as they try to find out the cause.


Bayo Ajibola

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